Cow Catcher

The Use of Antimalarial Drugs against Viral Infection

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  • ... The chemical inhibitors of mitogenactivated protein kinases (MAPK) were previously reported for their efficacy to reduce the phosphorylation of MAPKs as well as DENV-induced liver injury [34][35][36][37]. Recently, the FDA approved drugs including N-acetyl cysteine [38], minocycline [39], and quinine [40] were repurposed in DENV infection. In the current study, the role of AAK1 in DENV infection was investigated by sunitinib treatment in DENVinfected Huh7 cells. ...
     
     
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